The core gene of hepatits B virus; subtype adw2
نویسندگان
چکیده
منابع مشابه
Restriction endonuclease cleavage map and location of unique features of the DNA of hepatitis B virus, subtype adw2.
DNA of hepatitis B virus (HBV) of hepatitis B surface antigen (HBsAg) subtype adw2 made fully double stranded by the virion DNA polymerase and radiolabeled either by the virion DNA polymerase reaction or by nick-translation with 32P-labeled deoxynucleoside triphosphates was used to establish a map of restriction endonuclease cleavage sites by the method double and triple enzyme digestion and to...
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BACKGROUND AND AIMS Previous studies have demonstrated the dominance of genotype D subtype ayw in patients with hepatitis B virus infection in Turkey. The aim of the present study is to report, for the first time, genotype A2 subtype adw2 of hepatitis B virus in a patient who is an inactive hepatitis B carrier in Turkey. MATERIALS AND METHODS Hepatitis B virus DNA isolated from the serum samp...
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We have sequenced the complete genome of a hepatitis B virus (A938) obtained from serum of a patient with a high-titred, HBeAg-positive infection. The DNA sequence (3221 bp) was 99.2%, 95.4%, 90.9% and 89% homologous to the sequences of subtypes adw2 (3), adw (1), adr (5) and ayw (9). The adw2 subtype of the A938 virus was verified by analysing the subtype specific amino acids of the major surf...
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Background and Objective: Presence of hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) is defined, as isolated anti-HBc. little is known about the clinical significance of the isolated anti-HBc in hepatitis B virus (HBV) infections. The aim of this study was to assess the significance of anti-HBc as the onl...
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Recently we generated a panel of hepatitis B virus core gene mutants carrying single insertions or deletions which allowed efficient expression of the core protein in bacteria and self-assembly of capsids. Eleven of these mutations were introduced into a eukaryotic core gene expression vector and characterized by trans complementation of a core-negative HBV genome in cotransfected human hepatom...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1988
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/16.16.8188